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☆ FDA approves new drug that may help stop and even reverse a rare, fatal condition that doctors call a ‘ticking time bomb’
▼ + stars: | 2024-03-26 | by ( Brenda Goodman | ) edition.cnn.com time to read: +15 min

These proteins cause the walls of a person’s blood vessels to keep growing and thicken over time. As the blood vessels narrow, the heart is forced to work harder to pump blood to the lungs. Treatment with a combination of drugs that dilate, or relax, blood vessels can improve this outlook, but they are not a cure. Both groups were also taking the standard medications for the condition, which help relax blood vessels to improve blood flow. But Galiatsatos said that as promising as the drug looks, there are still many unknowns, including whether the drug will benefit all PAH patients equally.

Persons: Katrina Barry, Barry, “, ”, Winrevair, Merck Winrevair, Vallerie McLaughlin, Panagis, Galiatsatos, isn’t, ” Barry, I’m, fanny, She’s, sotatercept, PAH, Sotatercept, “ There’s, Kristin Highland, Highland, ” Merck, Merck, Dr, Sanjay Gupta, Aaron Waxman, Barry’s, he’s, they’ve, Johnson –, Waxman, “ I’ve, “ It’s, who’ve Organizations: CNN, American Lung Association, US Food and Drug Administration, Merck, FDA, University of Michigan, PAH, Johns Hopkins Bayview Medical Center, New England, of Medicine, Cleveland Clinic, Institute, Clinical, CNN Health, Brigham, Women’s Hospital, Johnson Locations: PAH, American, Greece, Boston

☆ What Zyn pouches do to your brain, body, and heart
▼ + stars: | 2024-02-16 | by ( Kim Schewitz | ) www.businessinsider.com time to read: +5 min

Zyn nicotine pouches are popping up everywhere. Someone using a 3 mg Zyn pouch will absorb 1.59 mg of nicotine, or 3.51 mg from a 6 mg pouch, a spokesperson for Zyn told Business Insider in an email. Middle and high-school-aged kids are using nicotine pouchesZyn says its products are only for consumers 21 and older who already use nicotine. However, unlike nicotine replacement therapies such as gum, patches, and mints, nicotine pouches like Zyn have not yet been proven to be a safe way to quit smoking. A 2023 study published by the Centers for Disease Control and Prevention found that around 1.5% of middle and high school students reported using nicotine pouches in the last 30 days.

Persons: Tucker Carlson, Bellini, Dr, Jonathan Foulds, Brittney Keller, Hamilto, Panagis, Alok Patel Organizations: Business, Penn State University College of Medicine, New York Times, Zyn, National Institute on Drug, Centers for Disease Control, CDC, The Ohio State University College of Medicine, Johns Hopkins Medicine, Stanford Children’s Hospital, ABC

☆ Fact Check-Inhaling hydrogen peroxide and iodine unsafe, and not a proven treatment for respiratory symptoms
▼ + stars: | 2023-01-23 | by ( Reuters Fact Check | ) www.reuters.com time to read: +5 min

Topical antiseptics such as hydrogen peroxide, iodine, or a combination of the two are not safe to inhale and not proven to treat respiratory infections, contrary to social media claims that breathing in these liquids is a good idea. Still, social media users are sharing a video that claims using a nebulizer to make a vapor from a mixture of hydrogen peroxide and iodine can treat respiratory infections like sore throat. Both hydrogen peroxide and iodine solutions are used on the skin, usually to prevent infection of minor cuts and scrapes (here). Evidence from studies of accidental inhalation shows that hydrogen peroxide can damage tissue and iodine can be toxic. There is no evidence that combining hydrogen peroxide and iodine in a nebulizer will treat respiratory symptoms, and the practice is potentially damaging and toxic, experts told Reuters.

☆ A promising new Covid pill shows key advantages over Paxlovid in trial
▼ + stars: | 2022-12-30 | by ( Aria Bendix | ) www.cnbc.com time to read: +2 min

A new antiviral pill for Covid was found to be as effective as Paxlovid at curbing mild to moderate illness among people at high risk of severe disease in a Phase 3 trial in China. The results, published Wednesday in The New England Journal of Medicine, suggest that the treatment had fewer side effects than Paxlovid, the go-to antiviral for high-risk patients. Around 67% of people who took the experimental pill, called VV116, reported side effects, compared to to 77% who took Paxlovid. In the trial of VV116, more than 380 people took the experimental drug, while a similarly sized group took Paxlovid. The median time to recovery — defined as no Covid symptoms for two consecutive days — was four days for VV116 recipients and five days for those who took Paxlovid.

Around 67% of people who took the experimental pill, called VV116, reported side effects, compared to to 77% who took Paxlovid. In the trial of VV116, more than 380 people took the experimental drug, while a similarly sized group took Paxlovid. The median time to recovery — defined as no Covid symptoms for two consecutive days — was four days for VV116 recipients and five days for those who took Paxlovid. Three-quarters of the trial participants were vaccinated, though the study found consistent results regardless of vaccine status. The National Institutes of Health recommends Paxlovid, with molnupiravir as an alternative in situations when neither Paxlovid nor remdesivir is available or appropriate.

The analysis by Canadian researchers, published Tuesday in Radiology, compared the chest scans of marijuana smokers and tobacco-only smokers who were matched according to age. Unlike cigarettes, joints aren’t filtered, and marijuana smokers inhale more deeply and longer than cigarette smokers do. The marijuana smokers were identified by a search through the Ottawa Hospital records, using the terms “marijuana” and “cannabis.” Then Revah and her colleagues determined which of the marijuana smokers had had the chest scan. They then searched for nonsmokers and the cigarette smokers who had received chest scans to compare to the marijuana smokers. The marijuana smokers were ages 20 to 73, the nonsmokers were ages 19 to 75, and the tobacco-only smokers were ages 50 to 71.

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